The Institute of Molecular Embryology and Genetics aims to contribute to society by promoting the integration of life and medical sciences from the viewpoint of developmental biology. This institute was founded in 1992, and extensively reorganized in 2000 and 2009. It has three divisions (Developmental Regulation, Stem Cell Research, and Organogenesis) consisting of 13 laboratories. Our research interests include: epigenetics, chromosome and protein regulation, DNA damage and repair, intercellular communications, ES and iPS cells, mesenchymal stem cells, hematopoietic differentiation, gametogenesis, brain morphogenesis, muscle regeneration, and kidney development. The 21st Century Center-of-Excellence (COE) Program (2002-2006), followed by the global COE Program (2007-2011), promoted the outstanding research and educational activities in the Institute. In addition, the Center for Organ Regeneration Research was launched in 2012 to realize regenerative medicine through scientific collaborations with the University Hospital. Furthermore, the Institute is selected as one of the Joint Usage/Research Centers in Japan, and supports the research community.